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Chinese colorectal cancer WES sequencing. Homo sapiens

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NIAID Data Ecosystem2026-03-14 收录
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To elucidate the significance of genetic indicators on the immune contexture, whole genome sequencing (WES) was performed on MSI-high (n = 12) and POLE-mutant (n = 6) individuals. Neoantigen prediction and depletion analysis revealed that MSI-high tumors generated a greater abundance of neoantigens and fewer immune escape events, resulting in stronger immunogenicity overall.

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2022-12-29
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