Microglia M1 polarization-related genes Ntng1 and Plekha7 in chronic intermittent hypoxia mice hippocampus were identified as pathological expression patterns of obstructive sleep apnea syndrome

This study aims to investigate the molecular and signaling mechanisms associated with cognitive impairment induced by chronic intermittent hypoxia (CIH) in mice by integrating single-nucleus RNA-sequencing (snRNA-seq) and Bulk RNA sequencing (Bulk RNA-seq)