Complex structure of prostaglandin D2 synthase at 2.25A.
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Complex structure of prostaglandin D2 synthase at 2.25A. Descriptor: 4-{[4-(4-fluoro-3-methylphenyl)-1,3-thiazol-2-yl]amino}-2-hydroxybenzoic acid, GLUTATHIONE, GLUTATHIONE-REQUIRING PROSTAGLANDIN D SYNTHASE, ... Authors: Hohwy, M, Spadola, L, Lundquist, B, von Wachenfeldt, K, Persdotter, S, Hawtin, P, Dahmen, J, Groth-Clausen, I, Folmer, R.H.A, Edman, K. Deposit date: 2007-09-28 Release date: 2008-04-15 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2.25 Å) Cite: Novel Prostaglandin D Synthase Inhibitors Generated by Fragment-Based Drug Design. J.Med.Chem., 51, 2008
分辨率为2.25埃的前列腺素D2合酶(prostaglandin D2 synthase)复合晶体结构。描述符：4-{[4-(4-氟-3-甲基苯基)-1,3-噻唑-2-基]氨基}-2-羟基苯甲酸、谷胱甘肽(Glutathione)、需谷胱甘肽前列腺素D合酶(GLUTATHIONE-REQUIRING PROSTAGLANDIN D SYNTHASE)、……作者：Hohwy M、Spadola L、Lundquist B、von Wachenfeldt K、Persdotter S、Hawtin P、Dahmen J、Groth-Clausen I、Folmer R.H.A、Edman K。存储日期：2007-09-28；发布日期：2008-04-15；最后修改日期：2023-12-13；测试方法：X射线衍射(X-RAY DIFFRACTION)（2.25埃）；引用文献：《通过基于片段的药物设计获得的新型前列腺素D合酶抑制剂》，《J.Med.Chem.》，第51卷，2008年
创建时间：
2007-09-28
