Primary effusion lymphoma (PEL) is caused by Kaposi's sarcoma-associated herpesvirus (KSHV) and frequently also harbors Epstein-Barr virus (EBV). The expression of KSHV- and, often, EBV-encoded microR

NIAID Data Ecosystem50

An Epstein–Barr-related herpesvirus from marmoset lymphomas

疱疹病毒致癌机制

非人灵长类病毒比较基因组学

Epstein–Barr virus (EBV) is implicated in the development of human B cell lymphomas and carcinomas. Although related oncogenic herpesviruses were believed to be endemic only in Old World primate speci

PubMed Central2001-01-30 更新40

Modelling aggressive prostate cancers of young men in immune-competent mice, driven by isogenic Trp53 alterations and Pten loss

前列腺癌动物模型

p53

Understanding prostate cancer onset and progression in order to rationally treat this disease has been critically limited by a dire lack of relevant pre-clinical animal models. We have generated a set

NIAID Data Ecosystem50

The Epstein-Barr virus induced tumor suppressor miR-34a is growth promoting in EBV-infected B cells. Homo sapiens

疱疹病毒致癌机制

B细胞淋巴瘤

Epstein-Barr virus (EBV) infection of primary human B cells drives their indefinite proliferation into lymphoblastoid cell lines (LCLs). B cell immortalization depends on expression of viral latency g

NIAID Data Ecosystem40

Transgenic expression of polyoma virus middle T antigen in the mouse prostate gives rise to carcinoma

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