Systems analysis of uterine microenvironment in Treg depleted pregnant mice at 12 days after fertilization

ChEBI2015-12-10 更新2026-07-12 收录

妊娠免疫调节

母胎界面微环境

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Systems analysis of uterine microenvironment in Treg depleted pregnant mice at 12 days after fertilization

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2015-12-10

B cells acquire a unique and differential transcriptomic profile during pregnancy in mice. B cells acquire a unique and differential transcriptomic profile during pregnancy in mice

妊娠免疫调节

B细胞转录组

Pregnancy significantly alters B cells development and function. B cell activation is initiated by antigens specific binding to the BCR, leading to an intricate signaling pathway responsible for B cel

NIAID Data Ecosystem60

Total uterus transcriptome after depletion of regulatory T cells at E8 of murine pregnancy. Total uterus transcriptome after depletion of regulatory T cells at E8 of murine pregnancy

妊娠免疫调节

转录组分析

Regulatory T cells (Tregs) contribute to successful pregnancy by promoting maternal-fetal tolerance. We depleted Tregs using diphtheria toxin (DT) in the Foxp3DTR mouse model after allogenic mating wi

NIAID Data Ecosystem60

Table_1_Deep Surveying of the Transcriptional and Alternative Splicing Signatures for Decidual CD8+ T Cells at the First Trimester of Human Healthy Pregnancy.xlsx

妊娠免疫调节

T细胞转录组与可变剪接

Decidual CD8+ (dCD8) T cells have been proposed to play important roles in immune protection against the invading pathogens and in tolerance toward the growing semi-allogeneic fetus during early pregn

NIAID Data Ecosystem30

Table_2_Clonally Expanded Decidual Effector Regulatory T Cells Increase in Late Gestation of Normal Pregnancy, but Not in Preeclampsia, in Humans.XLSX

妊娠免疫调节

子痫前期病理机制

Background: Regulatory T (Treg) cells are necessary for the maintenance of allogenic pregnancy. However, the repertoire of effector Treg cells at the feto-maternal interface in human pregnancy remains

NIAID Data Ecosystem60

Table_2_Progesterone Dampens Immune Responses in In Vitro Activated CD4+ T Cells and Affects Genes Associated With Autoimmune Diseases That Improve During Pregnancy.xlsx

妊娠免疫调节

自身免疫性疾病基因表达谱

The changes in progesterone (P4) levels during and after pregnancy coincide with the temporary improvement and worsening of several autoimmune diseases like multiple sclerosis (MS) and rheumatoid arth

NIAID Data Ecosystem50

Systems analysis of uterine microenvironment in Treg depleted pregnant mice at 12 days after fertilization

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