GNPS Xconnector: Retrieving and visualizing metabolites and pathways information from various database sources

The diversity of the metabolomics databases arises from the different data types included within the database originating from various sources and experiments can be confusing for biologists and researchers who need further manual investigation for the retrieved data. Xconnector is a software package designed to easily retrieve and visualize metabolomics data from different databases. A human leukemia cell line (HL-60) sample was analyzed to validate the use of Xconnector. The metabolites separation was carried out using a SCIEX Exion LCTM UHPLC system. Mass spectrometric analysis was performed using Triple TOFTM 5600+ system equipped with Duo-SprayTM source operated in the ESI mode.