Effect of chronic infection on survival to a secondary acute infection.

NIAID Data Ecosystem2026-03-11 收录

数据链接：

https://figshare.com/articles/dataset/Effect_of_chronic_infection_on_survival_to_a_secondary_acute_infection_/10043999 数据链接链接失效反馈

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资源简介：

Effect of chronic infection on survival to a secondary acute infection.

创建时间：

2019-10-24

BCL6-dependent TCF-1+ progenitor cells maintain effector and helper CD4 T cell responses to persistent antigen [ATAC-Seq]

T细胞免疫学

慢性感染免疫反应

Shortly after priming, the fate of activated CD4 T cells is segregated into BCL6+ follicular helper T (Tfh) and BCL6â effector (Teff) cells. However, it remains unknown how these subsets are sustain

NIAID Data Ecosystem50

data_sheet_1_Adaptive NKG2C+CD57+ Natural Killer Cell and Tim-3 Expression During Viral Infections.PDF

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慢性感染免疫反应

Repetitive stimulation by persistent pathogens such as human cytomegalovirus (HCMV) or human immunodeficiency virus (HIV) induces the differentiation of natural killer (NK) cells. This maturation path

NIAID Data Ecosystem50

Spatial RNA-sequencing of day7 and day 21 post-LCMV Cl13 infection following transient CD4+ T cell depletion (Visium). Spatial RNA-sequencing of day7 and day 21 post-LCMV Cl13 infection following transient CD4+ T cell depletion (Visium)

空间转录组学

慢性感染免疫反应

CD4+ T cells play a critical role in sustaining the effector function of CD8+ T cells during chronic viral infection. When CD4+ T cell “help” is absent, CD8+ T cells enter a dysfunctional state, losin

NIAID Data Ecosystem30

Macrophage and T Cell Produced IL-10 Promotes Viral Chronicity

慢性感染免疫反应

T细胞耗竭

Chronic viral infections lead to CD8+ T cell exhaustion, characterized by impaired cytokine secretion. Presence of the immune-regulatory cytokine IL-10 promotes chronicity of Lymphocytic Choriomeningi

NIAID Data Ecosystem50

BCL6-dependent TCF-1+ progenitor cells maintain effector and helper CD4 T cell responses to persistent antigen [ATAC-Seq]

T细胞分化

慢性感染免疫反应

Shortly after priming, the fate of activated CD4 T cells is segregated into BCL6+ follicular helper T (Tfh) and BCL6– effector (Teff) cells. However, it remains unknown how these subsets are sustained

NIAID Data Ecosystem30

Effect of chronic infection on survival to a secondary acute infection.

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