Crystal Structure of Dihydrofolate Reductase from Mycobacterium tuberculosis bound to NADP and SDDC Inhibitor SDDC-888
收藏Protein Data Bank Japan2024-05-22 更新2026-03-21 收录
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Crystal Structure of Dihydrofolate Reductase from Mycobacterium tuberculosis bound to NADP and SDDC Inhibitor SDDC-888 Descriptor: 4-(3-{4-[(2,4-diamino-6-ethylpyrimidin-5-yl)oxy]butoxy}phenyl)butanoic acid, Dihydrofolate reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2021-12-20 Release date: 2022-02-09 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (1.65 Å) Cite: Crystal Structure of Dihydrofolate Reductase from Mycobacterium tuberculosis bound to NADP and SDDC Inhibitor SDDC-888 to be published
结核分枝杆菌（Mycobacterium tuberculosis）来源的二氢叶酸还原酶（Dihydrofolate Reductase）与烟酰胺腺嘌呤二核苷酸磷酸（NADP）及SDDC抑制剂SDDC-888结合的晶体结构
描述项：4-(3-{4-[(2,4-二氨基-6-乙基嘧啶-5-基)氧基]丁氧基}苯基)丁酸、二氢叶酸还原酶、烟酰胺腺嘌呤二核苷酸磷酸（NADP）
作者：西雅图传染病结构基因组学中心（Seattle Structural Genomics Center for Infectious Disease, SSGCID）
存储日期：2021-12-20
发布日期：2022-02-09
最后修改日期：2024-05-22
实验方法：X射线衍射（X-RAY DIFFRACTION，1.65 Å）
引用信息：结核分枝杆菌二氢叶酸还原酶与NADP及SDDC抑制剂SDDC-888结合的晶体结构，待发表
创建时间：
2021-12-20
