Breast cancer patient-derived xenografts undergo adaptive remodeling while preserving tumor heterogeneity and architecture: supplementary and source data

This dataset contains supplementary tables, processed molecular data, and source data supporting the manuscript “Breast cancer patient-derived xenografts undergo adaptive remodeling while preserving tumor heterogeneity and architecture.” The files include clinical and pathological characteristics, targeted DNA-panel information, transcriptomic pathway definitions, molecular determinants of PDX engraftment, geometric network analysis, longitudinal molecular evolution during serial PDX propagation, spatial and orthotopic analyses, and transcriptomic source matrices. Raw RNA sequencing data are separately available through the NCBI Sequence Read Archive under BioProject accession PRJNA1507614.