Synthesis, Characterization and PK/PD Studies of a Series of Spirocyclic Pyranochromene BACE1 Inhibitors
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Synthesis, Characterization and PK/PD Studies of a Series of Spirocyclic Pyranochromene BACE1 Inhibitors Descriptor: (4R,4a'R,10a'R)-7'-(5-chloropyridin-3-yl)-3',4',4a',10a'-tetrahydro-1'H-spiro[1,3-oxazole-4,5'-pyrano[3,4-b]chromen]-2-amine, Beta-secretase 1, NICKEL (II) ION Authors: Vigers, G.P.A. Deposit date: 2014-03-31 Release date: 2014-05-14 Last modified: 2024-11-27 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Synthesis, characterization, and PK/PD studies of a series of spirocyclic pyranochromene BACE1 inhibitors. Bioorg.Med.Chem.Lett., 24, 2014
一系列螺环吡喃并色烯类BACE1抑制剂的合成、表征及药代动力学/药效动力学（PK/PD）研究 数据集描述项：(4R,4a'R,10a'R)-7'-(5-氯吡啶-3-基)-3',4',4a',10a'-四氢-1'H-螺[1,3-恶唑-4,5'-吡喃并[3,4-b]色烯]-2-胺、β-分泌酶1（Beta-secretase 1）、镍(II)离子 作者：Vigers, G.P.A. 入库日期：2014-03-31 发布日期：2014-05-14 最后修改日期：2024-11-27 研究方法：X射线衍射（X-RAY DIFFRACTION，1.8埃） 引用文献：《一系列螺环吡喃并色烯类BACE1抑制剂的合成、表征及药代动力学/药效动力学研究》，Bioorg.Med.Chem.Lett., 24, 2014
