The bacterium Corynebacterium glutamicum can produce ʟ-glutamic acid under certain growth conditions. ʟ-glutamic acid is used as a flavor enhancer, food supplement, or primary chemical raw material. I
We evolved the recoded "amberless" E. coli that is used for incorporating nonstandard amino acids at the TAG codon in the laboratory. We observed parallel mutations in folA (dihydrofolate reductase) t
2-Deoxy-scyllo-inosose (DOI) has been a valuable starting natural product for the manufacture of pharmaceuticals or chemical engineering resources such as pyranose catechol. DOI synthase, which uses g
Comparison of gene expression profile in E. coli BW25113 wild type and ldhA-pflB- double mutant growing microaerobically in M9 media containing 10 g/L Glucose Overall design: two samples: wild type an
Ralstonia eutropha H16 is well-known to produce poly(3-hydroxybutyrate) [P(3HB)], a kind of polyhydroxyalkanoates attracted as bio-based biodegradable plastics, efficiently as an energy storage materi
