Differential Expression Summary Statistics for Perturb-Seq datasets analyzed in Nadig et al, 2025 (Nature Genetics)

Tables with compiled results of differential expression analysis of five perturb-seq datasets described in Nadig et al, 2025 (Nature Genetics) and Replogle et al, 2020 (Cell):K562-Essential, perturbation of essential genes in K562 cellsRPE1-Essential, perturbation of essential genes in RPE1 cellsHepG2-Essential, perturbation of essential genes in HepG2 cellsJurkat-Essential, perturbation of essential genes in Jurkat cellsK562-GenomeWide, perturbation of all expressed genes in K562 cellsFor each experiment, three tables are provided, where columns indicate the perturbed genes, rows indicate the genes in which expression is measured, and entries indicate either log2FoldChanges, log2FoldChange standard errors, or unadjusted p values. For details on the estimation of these quantities, see the manuscript below.If you use these results in your work, please cite the manuscript below.Nadig, Ajay, Joseph M. Replogle, Angela N. Pogson, Mukundh Murthy, Steven A. McCarroll, Jonathan S. Weissman, Elise B. Robinson, and Luke J. O’Connor. "Transcriptome-wide analysis of differential expression in perturbation atlases." Nature Genetics (2025): 1-10.