Highly Selective FeCl<sub>3</sub>‑Catalyzed Cyclization of β‑Sulfonamidoallenes or β‑Allenols and Aldehydes
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A FeCl3-catalyzed Prins cyclization reaction of β-sulfonamidoallenes or β-allenols with aldehydes has been developed for the synthesis of 3-chloromethyl-1,2,5,6-tetrahydro-1H-pyridine or 3-chloromethyl-5,6-dihydro-2H-pyran. The reaction is highly selective due to the stability of the allyl cation intermediate.
创建时间:
2013-04-05



