Crystal structure of Nucleoside 2-deoxyribosyltransferase from Trypanosoma brucei at 1.7 A resolution with 5-Aminoisoquinoline bound
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Crystal structure of Nucleoside 2-deoxyribosyltransferase from Trypanosoma brucei at 1.7 A resolution with 5-Aminoisoquinoline bound Descriptor: GLYCEROL, ISOQUINOLIN-5-AMINE, Nucleoside 2-deoxyribosyltransferase, ... Authors: Bosch, J, Robien, M.A, Hol, W.G.J, Structural Genomics of Pathogenic Protozoa Consortium (SGPP) Deposit date: 2005-11-17 Release date: 2005-11-22 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Using fragment cocktail crystallography to assist inhibitor design of Trypanosoma brucei nucleoside 2-deoxyribosyltransferase. J.Med.Chem., 49, 2006
本数据集收录布氏锥虫(Trypanosoma brucei)来源的核苷2-脱氧核糖基转移酶(Nucleoside 2-deoxyribosyltransferase)的晶体结构,分辨率为1.7 Å,该结构结合了5-氨基异喹啉(5-Aminoisoquinoline)与甘油(GLYCEROL)。
标识项:甘油(GLYCEROL)、5-氨基异喹啉(5-Aminoisoquinoline)、核苷2-脱氧核糖基转移酶(Nucleoside 2-deoxyribosyltransferase)……
作者:Bosch, J、Robien, M.A、Hol, W.G.J,致病性原虫结构基因组学联盟(Structural Genomics of Pathogenic Protozoa Consortium, SGPP)
提交日期:2005-11-17
发布日期:2005-11-22
最后修改日期:2024-11-13
实验方法:X射线衍射(X-RAY DIFFRACTION, 1.7 Å)
引用文献:《利用片段组合结晶法辅助布氏锥虫核苷2-脱氧核糖基转移酶抑制剂设计》,《J.Med.Chem.》,第49卷,2006年
创建时间:
2005-11-17



