FAM83H-AS1 is a non-coding oncogenic driver and therapeutic target of lung adenocarcinoma
收藏NIAID Data Ecosystem2026-03-12 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP287504
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Our study suggested that FAM83H-AS1 was a potential oncogenic driver due to chromosome 8q24 amplification in lung adenocarcinoma. To investigate the molecular mechanism of FAM83H-AS1, we performed high-thoughput RNA sequencing (RNA-Seq) assays after the silence of FAM83H-AS1 in A549 cell lines. Overall design: In human lung adenocarcinoma A549 cells, we downregulated the expression of FAM83H-AS1 utilizing small interference RNA (siRNA) and used scrumble as negative control. Then we used RNA-Seq to reveal the change of mRNA profiles after the silence of FAM83H-AS1.
创建时间：
2021-03-01
