*Lambert et al., 2013 [11]. IGAP: International Genomics of Alzheimer's Project. Bolded OR indicates an OR more extreme than that reported by the IGAP paper [11]. Bolded p-value indicates a p-value si
The accumulation of amyloid beta (Aβ) peptide (Amyloid cascade hypothesis), an APP protein cleavage product, is a leading hypothesis in the etiology of Alzheimer's disease (AD). In order to identify a
The assay for transposase-accessible chromatin by sequencing (ATAC-seq) was used to investigate the AD-associated chromatin reshaping in the APPswe/PS1dE9 (APP/PS1) mouse model. ATAC-seq data in the h