In Escherichia coli, the CpxRA two-component signal transduction system senses and responds to aggregated and misfolded proteins in the bacterial envelope. We show that CpxR-P (the phosphorylated form

PubMed Central10

Hepatic transcriptome of mice with a deletion of the miR-379/miR-410 cluster obtained 4h following a caesarean at embryonic day E19.5

围产期代谢适应

效应基因调控

In placental mammals, adaptation to extra-uterine life requires complex metabolic adjustments linked to the abrupt transition from the transplacental transfer of glucose toward the use of fat originat

Alliance of Genome Resources00

Adaptive Variation Regulates the Expression of the Human SGK1 Gene in Response to Stress

效应基因调控

遗传变异与激素反应

The Serum and Glucocorticoid-regulated Kinase1 (SGK1) gene is a target of the glucocorticoid receptor (GR) and is central to the stress response in many human tissues. Because environmental stress var

NIAID Data Ecosystem20

METTL5, an 18S rRNA-specific m6A methyltransferase, modulates expression of stress response genes

RNA甲基化

效应基因调控

Input mRNAs and ribosome protected fragments (RPFs) from wildtype and Mettl5 knockout (KO) B16 cells were analyzed by TruSeq Ribo Profile (Illumina) library preparation and high throughput sequencing

NIAID Data Ecosystem10

The effects of cis-regulatory mutations in SUL1 on yeast sulfate-limited fitness. Saccharomyces cerevisiae

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