Genotype-specific senescence responses in HCT116 isogenic cell lines.

NIAID Data Ecosystem2026-03-10 收录

数据链接：

https://figshare.com/articles/dataset/Genotype-specific_senescence_responses_in_HCT116_isogenic_cell_lines_/5309332 数据链接链接失效反馈

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资源简介：

Genotype-specific senescence responses in HCT116 isogenic cell lines.

创建时间：

2017-08-24

m6A independent genome-wide METTL3 and METTL14 redistribution drives senescence-associated secretory phenotype [RNA-seq]

细胞衰老

基因表达调控

Methyltransferase-like 3 (METTL3) and 14 (METTL14) are core subunits of the methyltransferase complex (MTC) that catalyzes mRNA N6-methyladenosine (m6A) modification. Despite the expanding list of m6

干细胞与再生医学数据中心2022-02-20 更新120

Set 2_S3_filtered_gene

肾脏疾病

细胞衰老

Renal artery stenosis (RAS) engenders stenotic-kidney ischemia, dysfunction, and injury, but whether these are mediated by cellular senescence has not been elucidated. Using INK-ATTAC transgenic mice,

DataCite Commons2020-09-24 更新80

Additional file 3: Table S2. of A prototypical non-malignant epithelial model to study genome dynamics and concurrently monitor micro-RNAs and proteins in situ during oncogene-induced senescence

细胞衰老

RNA表达

Studies on miR expression in senescent cells. (XLSX 20Â kb)

DataCite Commons2020-08-31 更新60

Safeguarding nucleolar homeostasis by CBX4 alleviates senescence and osteoarthritis

细胞衰老

骨关节炎

Chromobox homolog 4 (CBX4), a component of polycomb repressive complexes 1 (PRC1), plays important roles in the maintenance of cell identity and organism development through epigenetic silencing. Howe

干细胞与再生医学数据中心2022-02-20 更新110

Additional file 3: Dataset 1. of Mapping H4K20me3 onto the chromatin landscape of senescent cells indicates a function in control of cell senescence and tumor suppression through preservation of genetic and epigenetic stability

表观遗传学

细胞衰老

Ranked list of the 500 genes containing the greatest H4K20me3 enrichment in RS cells. Dataset 2. Ranked list of the 500 genes containing the greatest H4K20me3 enrichment in OIS cells. (XLS 109 kb)

DataCite Commons2024-12-16 更新60

Genotype-specific senescence responses in HCT116 isogenic cell lines.

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