Evolution of virulence in Pseudomonas aeruginosa mouse chronic wound samples

NIAID Data Ecosystem2026-03-11 收录

细菌毒力演化

小鼠慢性伤口模型

数据链接：

https://www.ncbi.nlm.nih.gov/bioproject/PRJNA643594 数据链接链接失效反馈

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资源简介：

To test how virulence evolves in Pseudomonas aeruginosa when passaged through ten rounds of mice for forty-two days.

创建时间：

2020-07-01

Life History Trade-Offs and Relaxed Selection Can Decrease Bacterial Virulence in Environmental Reservoirs

细菌毒力演化

宿主-病原体相互作用

Pathogen virulence is usually thought to evolve in reciprocal selection with the host. While this might be true for obligate pathogens, the life histories of opportunistic pathogens typically alternat

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Genome Sequencing Reveals Unique Mutations in Characteristic Metabolic Pathways and the Transfer of Virulence Genes between V. mimicus and V. cholerae

病原体比较基因组学

细菌毒力演化

Vibrio mimicus, the species most similar to V. cholerae, is a microbe present in the natural environmental and sometimes causes diarrhea and internal infections in humans. It shows similar phenotypes

NIAID Data Ecosystem30

Long-term serial culture of Piscirickettsia salmonis leads to a genomic and transcriptomic reorganization affecting bacterial in vitro virulence

细菌毒力演化

鲑鱼疫苗开发

The propagation of intracellular bacteria in culture mediums implies physiological adaptation to an artificial environment. If these conditions are persistent enough time, a permanent adaptation to th

NIAID Data Ecosystem20

Isolation of a Staphylococcus aureus capsulated derivative after passage of non-encapsulated isolate HU-14 through the bloodstream using a mouse model of bacteremia.. Adaptation of S. aureus bone isolate to blood.

细菌毒力演化

宿主-病原体相互作用

Selection pressures exerted on Staphylococcus aureus by host factors during infection may lead to the emergence of regulatory phenotypes better adapted to the conditions encountered at the infection s

NIAID Data Ecosystem30

Klebsiella pneumoniae strain:JNQH373 | isolate:JNQH373 Genome sequencing. Klebsiella pneumoniae strain:JNQH373 | isolate:JNQH373

病原微生物基因组学

细菌毒力演化

To explore the virulence evolution and pathogenic mechanism of hypervirulent Klebsiella pneumoniae

NIAID Data Ecosystem20