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Formal [4 + 1]- and [5 + 1]-Annulation by an S<sub>N</sub>2–Conjugate Addition Sequence: Stereoselective Synthesis of Highly Substituted Carbocycles

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NIAID Data Ecosystem2026-03-07 收录
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K2CO3-mediated reactions of 6-bromo-2-hexenoates and 7-bromo-2-heptenoate with active methylene compounds deliver highly substituted cyclopentane and cyclohexane derivatives, respectively via a sequence of SN2–conjugate addition reactions (formal [4 + 1]- and [5 + 1]-annulation) in a diastereoselective manner.

创建时间:
2016-02-20
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