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Immunity to seasonal coronavirus spike proteins does not protect from SARS-CoV-2 challenge in a mouse model

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NIAID Data Ecosystem2026-05-10 收录
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Mice were vaccinated with the spike proteins of 229E, NL63, OC43, HKU1 and SARS-CoV-2 (expressed as soluble trimers) with an oil-in-water emulsion adjuvant in a prime-boost regimen. Control mice were vaccinated with an irrelevant recombinant antigen, recombinant influenza virus hemagglutinin (HA).

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2025-10-30
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