BindingDB Entry 12119: DEUTERATED DHODH INHIBITORS

Name: BindingDB Entry 12119: DEUTERATED DHODH INHIBITORS
Creator: BindingDB
Published: 2024-09-28T16:51:31+08:00

DataCite Commons2024-09-28 更新2025-04-16 收录

药物靶点结合

抑制剂优化

数据链接：

https://www.bindingdb.org/entry/12119 数据链接链接失效反馈

官方服务：

资源简介：

Small molecule binding data for protein Dihydroorotate dehydrogenase (quinone), mitochondrial, Uniprot Q02127

提供机构：

BindingDB

创建时间：

2024-09-28

Engineering Selectivity for Reduced Toxicity of Bacterial Kinase Inhibitors Using Structure-Guided Medicinal Chemistry

抑制剂优化

结核病药物研发

Tuberculosis is a major global public health concern, and new drugs are needed to combat both the typical form and the increasingly common drug-resistant form of this disease. The essential tuberculos

NIAID Data Ecosystem90

BindingDB Entry 50018236: Reversible Lysine Specific Demethylase 1 (LSD1) Inhibitors: A Promising Wrench to Impair LSD1.

药物发现

蛋白质结合

Small molecule binding data for protein Amine oxidase [flavin-containing] A, Amine oxidase [flavin-containing] B, Lysine-specific histone demethylase 1A, and REST corepressor 1, Uniprot O60341, P21397

DataCite Commons2024-04-26 更新70

From Cancer to Pain Target by Automated Selectivity Inversion of a Clinical Candidate

计算机辅助药物设计

抑制剂优化

Elimination of inadvertent binding is crucial for inhibitor design targeting conserved protein classes like kinases. Compounds in clinical trials provide a rich source for initiating drug design effor

NIAID Data Ecosystem50

BindingDB Entry 50018569: Discovery and Optimization of Potent and Orally Available CTP Synthetase Inhibitors for Use in Treatment of Diseases Driven by Aberrant Immune Cell Proliferation.

肿瘤药物靶点验证

抑制剂筛选

Small molecule binding data for protein CTP synthase 1 and CTP synthase 2, Uniprot P17812, P70303, P70698, Q5U2N0, and Q9NRF8

DataCite Commons2024-04-26 更新90

BindingDB Entry 50018636: Overview of piperlongumine analogues and their therapeutic potential.

配体-蛋白质相互作用

药物靶点筛选

Small molecule binding data for protein Aldo-keto reductase family 1 member B1, Uniprot P15121

DataCite Commons2024-04-26 更新70