five

Chip-chip from human epidermis with H3ac

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NIAID Data Ecosystem2026-03-12 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE104764
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The UV radiation induced epigenetic changes play an important role in photoaging, but experimental evidence of histone modification to support this perspective has been scarce. Analyse the histone H3 acetylation pattern in sun-exposed and non-exposed skin by ChIP-chip. 227 genes displayed significant histone H3 hyperacetylation and 81 genes displayed significant histone H3 hypoacetylation in sun-exposed skins. ChIP-chip assay with anti-acetyl-histone H3 antibody in sun-exposed Pool (combining six skin samples from the outer forearm) and non-exposed Pool (combining six skin samples from the buttock)
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2021-07-25
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