Crystal structure of the mutant D70N of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with 6-azauridine 5'-monophosphate

Crystal structure of the mutant D70N of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with 6-azauridine 5'-monophosphate Descriptor: 6-AZA URIDINE 5'-MONOPHOSPHATE, Orotidine 5'-phosphate decarboxylase Authors: Fedorov, A.A, Fedorov, E.V, Chan, K.K, Gerlt, J.A, Almo, S.C. Deposit date: 2009-01-30 Release date: 2009-06-23 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Mechanism of the orotidine 5'-monophosphate decarboxylase-catalyzed reaction: evidence for substrate destabilization. Biochemistry, 48, 2009

热自养甲烷杆菌（Methanobacterium thermoautotrophicum）来源的乳清苷5'-单磷酸脱羧酶（orotidine 5'-monophosphate decarboxylase）突变体D70N与6-氮尿苷5'-单磷酸（6-azauridine 5'-monophosphate）复合的晶体结构。描述符：6-氮尿苷5'-单磷酸、乳清苷5'-单磷酸脱羧酶。作者：Fedorov, A.A.、Fedorov, E.V.、Chan, K.K.、Gerlt, J.A.、Almo, S.C.。提交日期：2009-01-30，发布日期：2009-06-23，最后修改日期：2023-09-06。实验方法：X射线衍射（X-RAY DIFFRACTION，分辨率1.5 Å）。引用文献：《乳清苷5'-单磷酸脱羧酶催化反应的机制：底物去稳定化的证据》，《生物化学（Biochemistry）》，第48卷，2009年。