MST-312: a telomerase inhibitor effectively blocking MYC oncogenic functions
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2020-01-02
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Supplementary Material for: BIBR1532 affects endometrial cell proliferation, migration and invasion in endometriosis via telomerase inhibition and MAPK signaling
Objectives: The effect of telomerase inhibitor BIBR1532 on endometriotic cells was investigated to explore the inhibitory effect of targeting telomerase on endometriosis. Design: In vitro primary cell
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Supplementary Material for: BIBR1532 affects endometrial cell proliferation, migration and invasion in endometriosis via telomerase inhibition and MAPK signaling
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Telomeres, crucial for chromosomal integrity, have been related to aging and cancer formation, mainly through regulating G-quadruplex structures. G-quadruplexes are structural motifs that can arise as
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Exploring the Effect and Mechanisms of Telomerase Inhibition as A Novel Therapeutic Strategy for Glioma
The obejctive of this study is to establish the therapeutic role of 6-thio-dG for gliomas in vitro and in vivo and to elucidate the anti-tumor mechanisms of 6-thio-dG in glioma cells. And the ultimate
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