Effect of depletion of Suv39h1 on gene expression of TGF-β stimulated mouse primary renal fibroblasts
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE218814
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To investigate the the role of suv39h1 in the regulation of kidney fibrosis in vitro, we established suv39h1fl/fl mice and isolated renal fibroblasts.Fibroblasts were treated with Cre recombinant adenovirus (Ad-Cre) or GFP recombinant adenovirus(Ad-GFP) , and then TGF-β was added to the cells after starving overnight. Comparative gene expression profiling analysis of RNA-seq data for Ad-Cre treated renal fibroblasts and Ad-GFP treated fibroblasts. Fibroblast activation was induced by treatment with TGF-β.
创建时间：
2023-11-01
