Computational modeling has emerged as an indispensable approach to resolve and predict the intricate interplay among the many ion channels underlying neuronal excitability. However, simulation results
Persistent inward currents (PICs) play a crucial role in regulating neuronal excitability. These currents are composed of calcium (CaL) and sodium (NaP) components in vertebrate spinal neurons. Recent
Appendix. A0 Mean and Covariance as a Function of Kinetic Model Parameters. A1 Linear Algebra Algorithms for Semiseparable Matrices. A2 Log-likelihood Gradient. A3 Log-likelihood Calculation in the Ca