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A maternal effect regulates global DNA methylation patterns

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NIAID Data Ecosystem2026-03-12 收录
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Variation in DNA methylation between individuals is influenced by genetic and environmental factors, but their relative impact is largely unknown. Whole-genome, high-resolution methylation analysis in two mouse strains revealed striking differences in the global distribution of DNA methylation specifically at CpG island promoters and first exons. Interbreeding and cross-fostering experiments identified a maternal origin of these effects.

创建时间:
2021-02-04
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