Genome-wide identification and functional characterization of the 2,3-oxidosqualene cyclase gene family in loquat (Eriobotrya japonica Lindl.)

Triterpenoids are recognized as the main medicinal active substances in loquat, a plant that serves both medicinal and culinary purposes, with the synthesis of these compounds being critically dependent on the key enzyme OSC. The identification of 15 OSC proteins from the loquat genome was achieved in this study to further reveal the molecular functions of the loquat protein family. 15 CDS sequences of EjOSC genes were discovered, providing research genes for exploring the important role of the OSC gene family in the synthesis of triterpenoids.三萜类化合物是药食两用植物枇杷的主要药用活性物质，此类化合物的合成高度依赖关键酶角鲨烯环氧化酶（OSC）。本研究从枇杷基因组中鉴定出15个OSC蛋白，以进一步解析枇杷蛋白家族的分子功能；共发现15个EjOSC基因的CDS序列，可为探究OSC基因家族在三萜类化合物合成中的关键作用提供研究素材。