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Total Synthesis of (−)-5,6-Dihydrocineromycin B

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https://figshare.com/articles/dataset/Total_Synthesis_of_5_6_Dihydrocineromycin_B/2880268
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资源简介:
An asymmetric total synthesis of (−)-5,6-dihydrocineromycin B has been accomplished in 13 steps from (−)-linalool O-triethylsilyl ether or 12 steps from geraniol. The present synthesis features (i) an intermolecular Wittig reaction involving an aldehyde possessing a ketophosphonate functionality and (ii) an intramolecular Horner−Wadsworth−Emmons olefination.
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2009-02-06
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