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资源简介：
Leukemia Inhibitory Factor in C26 Cancer Cachexia
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创建时间：
2015-06-25
相关数据集
Progressive development of melanoma-induced cachexia differentially impacts organ systems in mice [Tumor]. Progressive development of melanoma-induced cachexia differentially impacts organ systems in mice [Tumor]
Cachexia is a systemic wasting syndrome that develops in many cancers and increases mortality. Despite its importance, it is largely unknown how cachexia progressively and differentially induces tissu
NIAID Data Ecosystem40
Expression data from murine adipose tissue endothelial cells during pre-cachexia
Endothelial cells form a barrier between the contents of the blood and adipocytes. We hypothesized that during cancer cachexia development, transcriptomic changes alter angiocrine signals to contribut
NIAID Data Ecosystem20
Kinome profiling of skeletal muscle from a mouse model of pancreatic cancer-induced cachexia
More than 85% of patients with pancreatic ductal adenocarcinoma (PDAC) suffer from cachexia, a debilitating syndrome characterized by loss of muscle and fat. To model PDAC cachexia in mice, 12-week-ol
NIAID Data Ecosystem20
Depletion of stromal cells expressing fibroblast activation protein-α from skeletal muscle and bone marrow results in cachexia and anemia
Fibroblast activation protein-α (FAP) identifies stromal cells of mesenchymal origin in human cancers and chronic inflammatory lesions. In mouse models of cancer, they have been shown to be immune sup
NIAID Data Ecosystem30
Methionine cycle dysregulation mediates REDD1 overexpression-induced muscle atrophy in cancer cachexia
The essential amino acid methionine plays a pivotal role in one-carbon metabolism, facilitating the production of S-adenosylmethionine (SAM), a critical supplier for DNA methylation and thereby a modu
Mendeley Data20
