Values are expressed as mean±SEM. In each group, values in parentheses represent n. *P<0.05 vs. age-matched shams. †P<0.05 vs. 4 wk shams. ACF: aortocaval fistula; HW: heart weight; BW: body weight; L
Mice with homozygous null mutations in the HDL receptor (SR-BI) and apoE genes (SR-BI KO/apoE double KO (dKO) mice) spontaneously develop occlusive, atherosclerotic coronary artery disease (CAD) and d