Univariable and multivariable proportional-hazards analysis of survival risk for three large independent testing sets*.

*Results for the datasets of van de Vijver, et al., and Wang, et al., represent 10 year Hazard Ratios (95%CI). Results for the dataset of Sorlie, et al. were calculated using all available data, which included 5 years of follow up. The endpoint for the van de Vijver analysis was overall survival and for the Wang and Sorlie analyses were relapse.#Multivariable analysis accounted for ER status and the 3D signature.aCI, confidence interval.