Endoplasmic reticulum aminopeptidase associated with antigen processing defines the composition and structure of MHC class I peptide repertoire in normal and virus-infected cells.
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To examine the impact of ER proteolysis in shaping the repertoire of antigenic peptides presented by MHC-I, naturally processed peptides were identified by mass spectrometry in ERAAP-/- versus WT C57BL/6 mouse spleen cells.
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IEDB创建时间：
2010-01-01
