Transforming Growth Factor-Ã (TGFÃ) Prevents Hypertension-Induced Aortic Dissection in Adult Mice via Extracellular Matrix Production (Bulk KO vs. WT SMC)
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https://www.ncbi.nlm.nih.gov/sra/SRP355990
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We report bulk RNA-seq data of Myh11 lineage marked smooth muscle cells (SMCs) from murine aortas at 1 week after conditional disruption of TGFÃ signaling versus controls Overall design: Thoracic aortas were procured from tamoxifen-treated, 12-week-old Myh11-CreERT2.mT/mG (designated as GFPiSMC or simply WT) or Tgfbr1f/f.Tgfbr2f/f.Myh11-CreERT2.mT/mG (designated as Tgfbr1/2iSMCKO or simply KO) mice, GFP+ SMCs were isolated after cryophilic enzyme digestion of thoracic aorta segments, and bulk RNA-seq analysis was performed
创建时间：
2025-07-01
