Ether Lipids in Adipose Tissue: Characterising their roles and therapeutic potential in metabolic disease

Plasmalogens are a specialised class of lipids synthesised by the body. They are vital for maintaining healthy cellular functions and are reduced in numerous Cardiometabolic diseases. Yvette's research delved into the mechanisms behind the decrease of plasmalogens in individuals with obesity and non-alcoholic fatty liver disease. By integrating innovative cell and animal models with human lipidomic datasets, her study aimed to uncover the therapeutic potential of elevating plasmalogen levels in disease contexts. Her findings shed light on the expansive impact of plasmalogens in both healthy and diseased states, underscoring their significance in the intricate regulation of whole-body homeostasis.