STRUCTURE AT 2.5-ANGSTROMS RESOLUTION OF CHEMICALLY SYNTHESIZED HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 PROTEASE COMPLEXED WITH A HYDROXYETHYLENE*-BASED INHIBITOR

STRUCTURE AT 2.5-ANGSTROMS RESOLUTION OF CHEMICALLY SYNTHESIZED HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 PROTEASE COMPLEXED WITH A HYDROXYETHYLENE*-BASED INHIBITOR Descriptor: HIV-1 PROTEASE, INHIBITOR VAL-SER-GLN-ASN-LEU-PSI(CH(OH)-CH2)-VAL-ILE-VAL (U-85548E) Authors: Jaskolski, M, Miller, M, Tomasselli, A.G, Sawyer, T.K, Staples, D.G, Heinrikson, R.L, Schneider, J, Kent, S.B.H, Wlodawer, A. Deposit date: 1990-10-26 Release date: 1993-10-31 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Structure at 2.5-A resolution of chemically synthesized human immunodeficiency virus type 1 protease complexed with a hydroxyethylene-based inhibitor. Biochemistry, 30, 1991化学合成人类免疫缺陷病毒1型（HIV-1）蛋白酶与羟乙烯基（hydroxyethylene）类抑制剂复合物的2.5埃分辨率晶体结构 描述项：HIV-1蛋白酶，抑制剂VAL-SER-GLN-ASN-LEU-PSI(CH(OH)-CH2)-VAL-ILE-VAL（U-85548E） 作者：Jaskolski, M、Miller, M、Tomasselli, A.G、Sawyer, T.K、Staples, D.G、Heinrikson, R.L、Schneider, J、Kent, S.B.H、Wlodawer, A. 提交日期：1990-10-26 发布日期：1993-10-31 最后修改日期：2023-11-15 实验方法：X射线衍射（2.5 Å） 引用文献：化学合成人类免疫缺陷病毒1型蛋白酶与羟乙烯基类抑制剂复合物的2.5埃分辨率晶体结构。《生物化学》，30卷，1991年