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Methylation profiling of dedifferentiated chondrosarcoma (DDCS) samples

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NIAID Data Ecosystem2026-03-14 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE214180
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Genome wide DNA methylation profiling of dedifferentiated chondrosarcoma samples. Genomic DNA was extracted from formalin-fixed paraffin-embedded (FFPE) tissue after manual macrodissection to ensure at least 10% tumor content, followed by bisulfite converstion. All samples were processed on the Infinium 850k array and scanned using the Illumina iScan, according to the manufacturer's recommended protocol. For methylation analysis, we included a total of 18 in-house DDCS cases, of which 7 samples were macrodissected well-differentiated chondrosarcoma components and 11 were macrodissected dedifferentiated components
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2023-04-02
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