Distribution of GC haplotype combinations and serum 25(OH)D concentrations in children, adults and all combined.

Bold numbers represent significant P values.Haplotype combinations were manually inferred and numbered. Homozygote haplotype combinations were numbered 11, 22, 33, 44 and 55. The combinations of the heterozygote haplotypes (12 to 45) were given by one number of each homozygote haplotype e.g. 1 + 2 = 12.1M major allele, m minor allele.2Raw geometric mean of serum 25(OH)D concentrations (nmol/L) and corresponding 95%-confidence interval.3Adjusted geometric mean of 25(OH)D concentrations (nmol/L) and corresponding 95%-confidence interval. Linear mixed models with family as a random factor, adjusted for age, sex, BMI, holiday, use of solarium, dietary vitamin D intake, use of multivitamin and vitamin D supplements.adjAdjusted P values. Haplotype combination 44 was excluded in the linear mixed model due to inadequate participants carrying this haplotype combination.