Supporting data for “Cocrystal Engineering of Pharmaceutical Solids: Preparation Methods, Characterization, and Therapeutic Potentials”.

Cocrystal engineering has gained tremendous popularity in the past decade thanks to its capability in modifying the pharmaceutical properties of drugs, including solubility, dissolution rate, stability, etc. Achieving efficient cocrystal screening has long been a paramount objective, especially when cocrystal formation is mediated by the amorphous intermediate phase. This folder contains the raw PXRD, DSC, and FTIR data for characterizing the successful synthesis of novel and elusive cocrystals. The cocrystals were obtained by different kinetic methods, such as rapid solvent removal and mechanical grinding. The data can facilitate the expansion of the solid-state landscape of pharmaceuticals.

在过去十年中，由于其在调节药物药理性质方面的卓越能力，包括溶解度、溶解速率、稳定性等，共晶工程学受到了极大的关注。高效共晶筛选的达成一直以来都是至关重要的目标，尤其是在共晶形成过程中由非晶态中间相介导的情况下。本文件夹包含了用于表征新型且难以捉摸的共晶体成功合成的原始PXRD、DSC和FTIR数据。这些共晶体通过不同的动力学方法获得，如快速溶剂去除和机械研磨。这些数据有助于拓展药物固态领域的视野。