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High-resolution epitope mapping by HX MS reveals the pathogenic mechanism and a possible therapy for autoimmune TTP syndrome.

Name: High-resolution epitope mapping by HX MS reveals the pathogenic mechanism and a possible therapy for autoimmune TTP syndrome.
Creator: IEDB
Published: 2026-05-21T14:28:44+08:00

ImmuneData2026-05-21 收录

自身免疫性TTP致病机制

单链抗体表位分析

数据链接：

https://immunedata.org/display-item.php?repository=0009&id=AWPTwT_3h18v6WY6Nh6M&query=%20 数据链接链接失效反馈

官方服务：

资源简介：

antibody name:scFv4-20

应用场景：

提供机构：

IEDB

免疫肽组学

HLA配体鉴定

The HLA-I-eluted immunopeptidome of the GR lymphoblastoid cell line (GR-LCL) was analyzed by a two-dimensional (2D) peptide prefractionation strategy followed by a hybrid peptide fragmentation method

ImmuneData50

Assessment of seasonal influenza A virus-specific CD4 T-cell responses to 2009 pandemic H1N1 swine-origin influenza A virus.

流感病毒免疫

疫苗效果评估

The epitope specific CD4+ T cell line proliferated in response to the Fluzone vaccine formulation from 2004-2005.

ImmuneData40

The memory phase of the CD4 T-cell response to influenza virus infection maintains its diverse antigen specificity.

流感病毒免疫记忆

CD4T细胞抗原特异性

T cell response was measured in CD4+ T cells, after 8-10 days, 30 days or 60 days post-infection.

ImmuneData30

HLA class II binding capacity of peptides derived from a panel of 32 common allergens.

过敏原表位

MHCII类结合分析

epitope description:GTGSLVITASMSGHI antigen name:Cla h 8 mhc allele name:HLA-DPB1*20:01

ImmuneData40

Loss in CD4 T-cell responses to multiple epitopes in influenza due to expression of one additional MHC class II molecule in the host.

T细胞免疫应答

MHC限制性

The epitope sequence was cited in Nayak et al. Viral Immunol. 2010 Apr;23(2):169-80 [PMID:20373997]. Similar results were seen for (B10 x B10.S) F1 mice (H-2bxs). Also, little apparent difference was

ImmuneData30

High-resolution epitope mapping by HX MS reveals the pathogenic mechanism and a possible therapy for autoimmune TTP syndrome.

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