Adam10

ENCODES a protein that exhibits metalloendopeptidase activity; endopeptidase activity (ortholog); metallodipeptidase activity (ortholog); INVOLVED IN amyloid-beta formation; positive regulation of apoptotic process; regulation of dendritic spine morphogenesis; PARTICIPATES IN epidermal growth factor/neuregulin signaling pathway; interleukin-6 signaling pathway; Notch signaling pathway; ASSOCIATED WITH Alzheimer's disease; cardiomyopathy; cataract; FOUND IN cell surface; dendrite; dendritic spine; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil

编码一种展现金属内肽酶活性的蛋白质；内肽酶活性（同源）；金属二肽酶活性（同源）；参与淀粉样β蛋白的形成；凋亡过程的正向调控；树突棘形态发生的调控；参与表皮生长因子/神经生长因子信号通路；白细胞介素-6信号通路；Delta/Notch信号通路；与阿尔茨海默病、心肌病、白内障相关；存在于细胞表面、树突、树突棘；与17β-雌二醇、2,3,7,8-四氯二苯并-对氧杂芑、6-丙基-2-硫尿嘧啶相互作用