Supporting data for “Study of the effect of Hirschsprung disease associated ephrinA1 and EphB2 mutations on cell-cell interaction“

Thesis figures and quantification data for the thesis entitled "Study of the effect of Hirschsprung disease associated ephrinA1 and EphB2 mutations on cell-cell interaction".The study aimed at investigating the functional role of Eph/ephrin signaling on ENCC colonization, the impact of the ephrinA1 and EphB2 mutations identified in Hirschsprung disease patients on cell-cell interaction and Eph/ephrin signaling mechanism. Stripe assay is used to examine the response of migraeting ENCCs upon interaction with Ephs and ephrins. Segregation assay is used to investigate the influence of the identified mutations on cell-cell interaction.

本数据集收录了题为《研究Hirschsprung病相关ephrinA1和EphB2突变对细胞间相互作用的影响》的论文中的插图和量化数据。研究旨在探讨Eph/ephrin信号通路在ENCC定植中的功能作用，以及Hirschsprung病患者中发现的ephrinA1和EphB2突变对细胞间相互作用及Eph/ephrin信号通路机制的影响。条带实验被用于检测迁移中的ENCC在与Ephs和ephrins相互作用后的反应。分离实验被用于研究所识别的突变对细胞间相互作用的影响。