Cross-sectional and longitudinal regression analyses in men: association of inflammation parameters with GFR/creatinine.

unadj. = unadjusted estimates; adj. = estimates adjusted for age, body mass index (BMI), HbA1c, low-density lipoprotein (LDL), high-density lipoprotein (HDL), baseline diastolic and systolic blood pressure and baseline to follow-up change in the longitudinal analyses, number of cigarettes/cigars/pipes smoked, presence of cardio-vascular diseases, regular intake of anti-diabetic (Anatomical Therapeutic Chemical Classification [ATC]: A10) and anti-hypertensive medication (ATC: C02/C03/C07/C08/C09); users coded as “1”, non-users coded as “0”. GFR estimated by means of CKD-EPI formula10. Effect estimates with 95% confidence intervals are displayed.*Effect estimates refer to an increase of one standard deviation in the log-transformed inflammation parameter.Abbreviations: sTNF-R1: Soluble tumour necrosis factor-α receptor 1; hsCRP: High-sensitivity C-reactive protein; IL-6: Interleukin 6; eGFR: estimated glomerular filtration rate.Cross-sectional and longitudinal regression analyses in men: association of inflammation parameters with GFR/creatinine.