Tanscriptome-wide mRNA and miRNA sequencing of AML KG-1 cells treated with decitabine (DAC) and all-trans retinoic acid (ATRA)

This study aimed to investigate the efficacy and mechanism of decitabine (DAC) and all-trans retinoic acid (ATRA) in AML cells. When KG-1 cells were treated with DAC and ATRA, matching concentrations of vehicle were used as the control. Tanscriptome-wide mRNA and miRNA sequencing were used to identify differentially expressed genes and miRNAs.