Crystal structure of a thermostabilised human protease-activated receptor-2 (PAR2) in complex with AZ8838 at 2.8 angstrom resolution
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Crystal structure of a thermostabilised human protease-activated receptor-2 (PAR2) in complex with AZ8838 at 2.8 angstrom resolution Descriptor: (~{S})-(4-fluoranyl-2-propyl-phenyl)-(1~{H}-imidazol-2-yl)methanol, Lysozyme,Proteinase-activated receptor 2,Soluble cytochrome b562,Proteinase-activated receptor 2, PHOSPHATE ION, ... Authors: Cheng, R.K.Y, Fiez-Vandal, C, Schlenker, O, Edman, K, Aggeler, B, Brown, D.G, Brown, G, Cooke, R.M, Dumelin, C.E, Dore, A.S, Geschwindner, S, Grebner, C, Hermansson, N.-O, Jazayeri, A, Johansson, P, Leong, L, Prihandoko, R, Rappas, M, Soutter, H, Snijder, A, Sundstrom, L, Tehan, B, Thornton, P, Troast, D, Wiggin, G, Zhukov, A, Marshall, F.H, Dekker, N. Deposit date: 2017-03-08 Release date: 2017-05-03 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (2.801 Å) Cite: Structural insight into allosteric modulation of protease-activated receptor 2. Nature, 545, 2017
分辨率为2.8埃的热稳定人源蛋白酶激活受体2（protease-activated receptor 2，PAR2）与AZ8838形成复合物的晶体结构
组分：(S)-(4-氟-2-丙基苯基)-(1H-咪唑-2-基)甲醇、溶菌酶、蛋白酶激活受体2、可溶性细胞色素b562、磷酸根离子……
作者：Cheng, R.K.Y、Fiez-Vandal, C、Schlenker, O、Edman, K、Aggeler, B、Brown, D.G、Brown, G、Cooke, R.M、Dumelin, C.E、Dore, A.S、Geschwindner, S、Grebner, C、Hermansson, N.-O、Jazayeri, A、Johansson, P、Leong, L、Prihandoko, R、Rappas, M、Soutter, H、Snijder, A、Sundstrom, L、Tehan, B、Thornton, P、Troast, D、Wiggin, G、Zhukov, A、Marshall, F.H、Dekker, N
提交日期：2017-03-08
发布日期：2017-05-03
最后更新日期：2024-10-16
实验方法：X射线衍射（分辨率2.801埃）
引用文献：《蛋白酶激活受体2的变构调节结构解析》，《自然》（*Nature*），第545卷，2017年
创建时间：
2017-03-08
