Functional associations of discriminant proteins used to generate SOMs.

Figures illustrating each SOM and the classes compared in each are indicated. Where more than two classes were compared (columns 1, 4, 7 and 8), only those proteins common to all comparisons are listed; complete lists of proteins for each comparison are provided in S1 and S2 Tables. MAPK, components of the MAP kinase pathway; MTOR, components of the mechanistic target of rapamycin pathway; AD, proteins observed to be abnormal in brains from patients with or mouse models of Alzheimer’s Disease; NMDAR, subunits of ionotropic glutamate receptors and interacting proteins; Hsa21, proteins encoded by human chromosomes 21; IEG, immediate early gene proteins; apoptosis-related, BAD, proapoptotic, BCL2, antiapoptotic; histone, histone protein H3 modifications: Ac, acetylation, Me, methylation, K amino acid number of modified lysine residue; Misc, miscellaneous.
Functional associations of discriminant proteins used to generate SOMs.