The RNA exosome nuclease complex regulates human embryonic stem cell differentiation [PAR-iCLIP]
收藏干细胞与再生医学数据中心2022-02-20 更新2024-03-06 收录
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This work shows that the exosome modulates the levels of LINE-1 retrotransposons, miRNAs, lncRNAs and specific mRNAs that encode developmental regulators or affect their expression. The exosome restrains differentiation in part by degrading transcripts encoding FOXH1, a transcription factor crucial for mesendoderm formation.
提供机构：
NIH
创建时间：
2022-02-20
