Effects of Cs on temperature response of C. borealis pyloric rhythm
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Motor systems operate over a range of frequencies and relative timing (phase). We studied the contribution of the hyperpolarization-activated inward current (Ih) to frequency and phase in the pyloric rhythm of the stomatogastric ganglion (STG) of the crab, Cancer borealis as temperature was altered from 11°C to 21°C. Under control conditions, the frequency of the rhythm increased monotonically with temperature, while the phases of the pyloric dilator (PD), lateral pyloric (LP), and pyloric (PY) neurons remained constant. When we blocked Ih with cesium (Cs+) PD offset, LP onset, and LP offset were all phase advanced in Cs+ at 11°C, and the latter two further advanced as temperature increased. In Cs+ the steady state increase in pyloric frequency with temperature diminished and the Q10 of the pyloric frequency dropped from ~1.75 to ~1.35. Unexpectedly in Cs+, the frequency displayed non-monotonic dynamics during temperature transitions; the frequency initially dropped as temperature incre..., The data consist largely of the spike times for various pyloric neurons recorded extra or intracellularly. These data were used to calculate feartures like frequency of the rhythm and phase of the components under various conditions. , , # Data from: Effects of Cs on temperature response of *C. borealis* pyloric rhythm
[https://doi.org/10.5061/dryad.1rn8pk129](https://doi.org/10.5061/dryad.1rn8pk129)
## Description of the data and file structure
Voltage Clamp Data: Contained in VoltageClampData.mat. VoltageClampData has 10 structures, one for each experiment. Each structure has 5 structures. ConditionDescriptions: describes the conditions of the trials in a given experiment. This includes information on the cell type (PD, LP), approximate temperature, and any Cs and/or other channel blockers like TTX or PTX. ConditionKey: Tells which rows of Voltage and Current correspond to which Condition. E.g., a \"4\" in position 6 says that the 6th row of Voltage and current has the 4th condition in ConditionDescriptions. Time: Index of time in seconds for every trial. Voltage: Trials x steps x time for the voltage. Each trial consisted of multiple voltage steps, usually in the range -60:-10:-120. Current: Same format as voltage b...
创建时间:
2024-08-10



