Crystal structure of HrmJ from Streptomyces sp. CFMR 7 (HrmJ-ssc) complexed with manganese (II), 2-oxoglutarate and 6-nitronorleucine

Crystal structure of HrmJ from Streptomyces sp. CFMR 7 (HrmJ-ssc) complexed with manganese (II), 2-oxoglutarate and 6-nitronorleucine Descriptor: 1,2-ETHANEDIOL, 2-OXOGLUTARIC ACID, 6-nitro-L-norleucine, ... Authors: Zheng, Y.-C, Swartz, P, Chang, W.-C. Deposit date: 2024-09-23 Release date: 2025-02-12 Last modified: 2025-03-05 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Comparison of a Nonheme Iron Cyclopropanase with a Homologous Hydroxylase Reveals Mechanistic Features Associated with Distinct Reaction Outcomes. J.Am.Chem.Soc., 147, 2025来自链霉菌属（Streptomyces）菌株CFMR 7的HrmJ蛋白（HrmJ-ssc）与二价锰离子、2-氧代戊二酸及6-硝基正亮氨酸结合的复合物晶体结构。配体描述：1,2-乙二醇、2-氧代戊二酸、6-硝基-L-正亮氨酸等。作者：Zheng, Y.-C、Swartz, P、Chang, W.-C。提交日期：2024-09-23；发布日期：2025-02-12；最后修改日期：2025-03-05。实验方法：X射线衍射（1.9 Å）。引用文献：《非血红素铁环丙烷化酶与同源羟化酶的比较：揭示与不同反应结果相关的机制特征》，《美国化学会志》（J.Am.Chem.Soc.），147卷，2025年